At 11.25pm on Friday 24 January 2014, police were called by the ambulance service after a 23-year-old man had been stabbed in the shoulder on Mond Road.
Another man, a 25 year-old, had received an injury to his hand.
Following inquiries by police, five men aged 25, 24, 23, 22 and 19 were arrested on suspicion of violent disorder and remain in police custody for questioning.
Detective Chief Inspector Clare Devlin said: “Clearly the news that a man has been stabbed will come as a shock to residents living in that area but I can reassure them that arrests were swiftly made following the incident.
“The man who was stabbed is in a serious but stable condition and I would ask anyone who saw what happened to come forward. From what we understand, there was an earlier altercation between a group of men and the two victim’s at the Railway Pub in Irlam.”
Anyone with information should phone police on 101 or the independent charity Crimestoppers, anonymously, on 0800 555 111.