Officers were called to the A912 at Bridge of Earn this morning following a collision between a white Ford Transit van and a motorbike.
The collision took place at about 7.45am at the junction with the northbound slip road to the M90.
The motorcyclist, a 25 year old man, sustained serious but not life threatening injuries and has been taken by ambulance to Ninewells Hospital in Dundee.
The road from the A912 Bridge of Earn to the M90 northbound is currently closed to allow crash investigators to work at the scene. Diversions are in place.
Anyone who witnessed the collision take place should get in touch with Police Scotland Tayside Division on 101 or speak to any police officer.